The Morphine or Ketamine for Analgesia Trial (MOKA)

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The Morphine or Ketamine for Analgesia Trial (MOKA)

Health Condition: Opioid use
Health Impact Domain: -

Summary

Our long-term goal is to improve the management of pain in children presenting to the ED with acute pain. The short-term goal of this application is to evaluate the efficacy of IV sub-dissociative ketamine compared to IV morphine for treating pain in children who most commonly receive parenteral opioids in the ED, namely those with abdominal pain or extremity fractures. The central hypothesis is that IV sub-dissociative ketamine is non-inferior to IV morphine for safely reducing pain intensity in children with moderate to severe pain and improves long-term patient outcomes.

Key Publications

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