Evaluating Tranexamic Acid (TXA) in Children with Traumatic Injuries (TIC-TOC)
Evaluating Tranexamic Acid (TXA) in Children with Traumatic Injuries (TIC-TOC)
Health Categories:
Trauma
Summary
This pilot and feasibility study is a double-blind, randomized controlled trial of 40 patients to provide safety and efficacy data on the use of TXA in severely injured children with torso and/or head injuries. Recent evidence in injured adults indicates that treatment with tranexamic acid (TXA) decreases mortality and blood-transfusion requirements following traumatic hemorrhage; however, TXA has not been appropriately studied in children with hemorrhagic injuries.
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