Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC) (TIC TOC Main)

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Traumatic Injury Clinical Trial Evaluating Tranexamic Acid in Children (TIC-TOC) (TIC TOC Main)

Health Condition: Trauma
Health Impact Domain: Mortality, Safety of care, Effectiveness of care, Timeliness of care, Decreased incidence/length of hospitalization

Summary

This pilot and feasibility study is a double-blind, randomized controlled trial of 40 patients to provide safety and efficacy data on the use of TXA in severely injured children with torso and/or head injuries. Recent evidence in injured adults indicates that treatment with tranexamic acid (TXA) decreases mortality and blood-transfusion requirements following traumatic hemorrhage; however, TXA has not been appropriately studied in children with hemorrhagic injuries.

Key Publications

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Related Media

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