Improving Detection of STIs in PEDs ED: A Pragmatic Trial (Adolescent STI)

Determine the most clinically effective and cost-effective sexually transmitted infections (STI) screening approach for adolescents using 3 steps: perform ED workflow evaluations to determine the most efficient way to integrate the screening process; conduct a comparative effectiveness pragmatic trial of targeted STI screening versus universally-offered STI screening through electronic integration of patient reported data for provision of clinical decision support; develop decision analytic models to evaluate the cost-effectiveness of targeted screening compared to universally offered screening. Adolescents are disproportionately affected by sexually transmitted infections and account for 9 million of the 19 million new STI cases annually. The STI epidemic among youth is a national public health priority. Despite established principles for STI control, clinical practices related to screening and diagnosis, treatment, and prevention of STIs among adolescents are suboptimal.